Botany · Principles of Inheritance and Variation

NEET (UG) 2023 — Question 113

Which of the following statements are correct about Klinefelter's Syndrome?

A. This disorder was first described by Langdon Down (1866).

B. Such an individual has overall masculine development. However, the feminine development is also expressed.

C. The affected individual is short statured.

D. Physical, psychomotor and mental development is retarded. E. Such individuals are sterile.

Choose the correct answer from the options given below :

Answer: B

Klinefelter's syndrome is caused due to the presence of an additional copy of X-chromosome

resulting into a karyotype of 47, XXY. Such an individual has overall masculine development,

however, the feminine development is also expressed. Such individuals are sterile.

Thus, statement B and E are correct regarding Klinefelter's syndrome.

Statement A, C and D are incorrect w.r.t. Klinefelter’s syndrome as they are associated

with Down’s syndrome.

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