JEE Main 2025 — 22 January, Morning Shift — Question 11

We need 5 letters with M as the middle (third) when sorted alphabetically. Choose 2 letters from the 12 before M (A to L): $\binom{12}{2}=66$ ways. Choose 2 letters from the 13 after M (N to Z): $\binom{13}{2}=78$ ways. Since the letters are arranged in alphabetical order once chosen, the total number of ways is $66 \times 78 = 5148$. Hence the answer is D.